Granulocyte-Macrophage Colony-Stimulating Factor Expressed by Recombinant Respiratory Syncytial Virus Attenuates Viral Replication and Increases the Level of Pulmonary Antigen-Presenting Cells

An obstacle to developing a vaccine against human respiratory syncytial virus (RSV) is that natural infection typically does not confer solid immunity to reinfection. To investigate methods to augment the immune response, recombinant RSV (rRSV) was constructed that expresses murine granulocyte-macro...

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Detalhes bibliográficos
Main Authors: Bukreyev, Alexander, Belyakov, Igor M., Berzofsky, Jay A., Murphy, Brian R., Collins, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116109/
https://ncbi.nlm.nih.gov/pubmed/11711604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12128-12140.2001
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