Granulocyte-Macrophage Colony-Stimulating Factor Expressed by Recombinant Respiratory Syncytial Virus Attenuates Viral Replication and Increases the Level of Pulmonary Antigen-Presenting Cells

An obstacle to developing a vaccine against human respiratory syncytial virus (RSV) is that natural infection typically does not confer solid immunity to reinfection. To investigate methods to augment the immune response, recombinant RSV (rRSV) was constructed that expresses murine granulocyte-macro...

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Autores principales: Bukreyev, Alexander, Belyakov, Igor M., Berzofsky, Jay A., Murphy, Brian R., Collins, Peter L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC116109/
https://ncbi.nlm.nih.gov/pubmed/11711604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12128-12140.2001
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