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Structural characterization of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase in its apo-form and in complex with 8-oxodeoxyguanosine
DNA is subject to a multitude of oxidative damages generated by oxidizing agents from metabolism, from exogenous sources and by ionizing radiation. Guanine is particularly vulnerable to oxidation and the most common oxidative product, 8-oxoguanine (8-oxoG), is the most prevalent lesion observed in D...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678946/ https://ncbi.nlm.nih.gov/pubmed/19361427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.067 |
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