Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth

Neovascularization in response to tissue injury consists of the dual invasion of blood (hemangiogenesis) and lymphatic (lymphangiogenesis) vessels. We reported recently that 21-nt or longer small interfering RNAs (siRNAs) can suppress hemangiogenesis in mouse models of choroidal neovascularization a...

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Detalles Bibliográficos
Autores principales: Cho, Won Gil, Albuquerque, Romulo J. C., Kleinman, Mark E., Tarallo, Valeria, Greco, Adelaide, Nozaki, Miho, Green, Martha G., Baffi, Judit Z., Ambati, Balamurali K., De Falco, Massimo, Alexander, Jonathan S., Brunetti, Arturo, De Falco, Sandro, Ambati, Jayakrishna
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678451/
https://ncbi.nlm.nih.gov/pubmed/19359485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812317106
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