Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth

Neovascularization in response to tissue injury consists of the dual invasion of blood (hemangiogenesis) and lymphatic (lymphangiogenesis) vessels. We reported recently that 21-nt or longer small interfering RNAs (siRNAs) can suppress hemangiogenesis in mouse models of choroidal neovascularization a...

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Bibliografiske detaljer
Main Authors: Cho, Won Gil, Albuquerque, Romulo J. C., Kleinman, Mark E., Tarallo, Valeria, Greco, Adelaide, Nozaki, Miho, Green, Martha G., Baffi, Judit Z., Ambati, Balamurali K., De Falco, Massimo, Alexander, Jonathan S., Brunetti, Arturo, De Falco, Sandro, Ambati, Jayakrishna
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678451/
https://ncbi.nlm.nih.gov/pubmed/19359485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812317106
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