Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth

Neovascularization in response to tissue injury consists of the dual invasion of blood (hemangiogenesis) and lymphatic (lymphangiogenesis) vessels. We reported recently that 21-nt or longer small interfering RNAs (siRNAs) can suppress hemangiogenesis in mouse models of choroidal neovascularization a...

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Detalhes bibliográficos
Main Authors: Cho, Won Gil, Albuquerque, Romulo J. C., Kleinman, Mark E., Tarallo, Valeria, Greco, Adelaide, Nozaki, Miho, Green, Martha G., Baffi, Judit Z., Ambati, Balamurali K., De Falco, Massimo, Alexander, Jonathan S., Brunetti, Arturo, De Falco, Sandro, Ambati, Jayakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678451/
https://ncbi.nlm.nih.gov/pubmed/19359485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812317106
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