Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase

The APOBEC3 proteins form a multigene family of cytidine deaminases with inhibitory activity against viruses and retrotransposons. In contrast to APOBEC3G (A3G), APOBEC3A (A3A) has no effect on lentiviruses but dramatically inhibits replication of the parvovirus adeno-associated virus (AAV). To stud...

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Bibliografiska uppgifter
Huvudupphovsmän: Narvaiza, Iñigo, Linfesty, Daniel C., Greener, Benjamin N., Hakata, Yoshiyuki, Pintel, David J., Logue, Eric, Landau, Nathaniel R., Weitzman, Matthew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678267/
https://ncbi.nlm.nih.gov/pubmed/19461882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000439
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