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Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent
Cytidine deamination is the primary mechanism by which APOBEC3G restricts HIV-1; however, several studies have reported that APOBEC3G also inhibits virus replication via a mechanism that is independent of deamination. Using active site APOBEC3G mutants, we have re-evaluated the biological relevance...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708462/ https://ncbi.nlm.nih.gov/pubmed/19304304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.026 |
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