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Host Restriction of Murine Gammaherpesvirus 68 Replication by Human APOBEC3 Cytidine Deaminases but Not Murine APOBEC3

Humans encode seven APOBEC3 (A3A-A3H) cytidine deaminase proteins that differ in their expression profiles, preferred nucleotide recognition sequence and capacity for restriction of RNA and DNA viruses. We identified APOBEC3 hotspots in numerous herpesvirus genomes. To determine the impact of host A...

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Detalhes bibliográficos
Main Authors: Minkah, Nana, Chavez, Kevin, Shah, Parth, MacCarthy, Thomas, Chen, Hui, Landau, Nathaniel, Krug, Laurie T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036618/
https://ncbi.nlm.nih.gov/pubmed/24725948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.02.022
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