The dapE-encoded N-succinyl-L,L-Diaminopimelic Acid Desuccinylase from Haemophilus influenzae Contains two Active Site Histidine Residues

The catalytic and structural properties of the H67A and H349A altered dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) from H. influenzae were investigated. Based on sequence alignment with CPG(2) both H67 and H349 were predicted to be Zn(II) ligands. Catalytic activity was obser...

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Autores principales: Gillner, Danuta M., Bienvenue, David L., Nocek, Boguslaw P., Joachimiak, Andrzej, Zachary, Vincentos, Bennett, Brian, Holz, Richard C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678232/
https://ncbi.nlm.nih.gov/pubmed/18712420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-008-0418-z
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