Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril

Binding of the competitive inhibitor L-captopril to the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Neisseria meningitidis (NmDapE) was examined by kinetic, spectroscopic, and crystallographic methods. L-Captopril, an angiotensin-converting enzyme (ACE) inhibitor, was previous...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Starus, Anna, Nocek, Boguslaw, Bennett, Brian, Larrabee, James A., Shaw, Daniel L., Sae-Lee, Wisath, Russo, Marie T., Gillner, Danuta M., Makowska-Grzyska, Magdalena, Joachimiak, Andrzej, Holz, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671288/
https://ncbi.nlm.nih.gov/pubmed/26186504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00475
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