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Structural Basis for Catalysis by the Mono and Dimetalated forms of the dapE-encoded N-succinyl-L,L-Diaminopimelic Acid Desuccinylase

Biosynthesis of lysine and meso-diaminopimelic acid in bacteria provides essential components for protein synthesis and construction of the bacterial peptidoglycan cell wall. The dapE operon enzymes synthesize both meso-diaminopimelic acid and lysine and, therefore, represent a potential targets for...

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Detalhes bibliográficos
Main Authors: Nocek, Boguslaw P., Gillner, Danuta M., Fan, Yao, Holz, Richard C., Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885003/
https://ncbi.nlm.nih.gov/pubmed/20138056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.062
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