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The Unfolded Protein Response of B-Lymphocytes: PERK-independent Development of Antibody-Secreting Cells

When B-lymphocytes differentiate into plasma cells, immunoglobulin (Ig) heavy and light chain synthesis escalates and the entire secretory apparatus expands to support high-rate antibody secretion. These same events occur when murine B-cells are stimulated with lipopolysaccharide (LPS), providing an...

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Autors principals: Gass, Jennifer N., Jiang, Hao-Yuan, Wek, Ronald C., Brewer, Joseph W.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677759/
https://ncbi.nlm.nih.gov/pubmed/17822768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.07.029
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