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The Specialized Unfolded Protein Response of B Lymphocytes: ATF6α-Independent Development of Antibody-Secreting B cells

B lymphocytes, like all mammalian cells, are equipped with the unfolded protein response (UPR), a complex signaling system allowing for both pro- and mal-adaptive responses to increased demands on the endoplasmic reticulum (ER). The UPR is comprised of three signaling pathways initiated by the ER tr...

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Detalhes bibliográficos
Main Authors: Aragon, Ileana V., Barrington, Robert A., Jackowski, Suzanne, Mori, Kazutoshi, Brewer, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358488/
https://ncbi.nlm.nih.gov/pubmed/22555069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.04.001
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