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The Unfolded Protein Response of B-Lymphocytes: PERK-independent Development of Antibody-Secreting Cells
When B-lymphocytes differentiate into plasma cells, immunoglobulin (Ig) heavy and light chain synthesis escalates and the entire secretory apparatus expands to support high-rate antibody secretion. These same events occur when murine B-cells are stimulated with lipopolysaccharide (LPS), providing an...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677759/ https://ncbi.nlm.nih.gov/pubmed/17822768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.07.029 |
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