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Phosphatidylcholine as a metabolic cue for determining B cell fate and function
In activated B cells, increased production of phosphatidylcholine (PtdCho), the most abundant cellular phospholipid, is handled primarily by the CDP-choline pathway. B cell-specific deletion of CTP:phosphocholine cytidylyltransferase α (CCTα), the rate-limiting enzyme in the CDP-choline pathway, led...
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| Publicado no: | Cell Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125835/ https://ncbi.nlm.nih.gov/pubmed/27502364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2016.08.002 |
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