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Effects of tyrosine mutations on the conformational and oxidative folding of ribonuclease A; A comparative study

Ribonuclease A (RNase A) undergoes more rapid conformational folding with its disulfide bonds intact than during oxidative folding from its reduced form. In this study, the effect of the mutants Y92G, Y92A, and Y92L on both the conformational and oxidative folding pathways was examined in order to d...

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Autors principals: Gahl, Robert F., Pradeep, Lovy, Siegel, Corey R., Xu, Guoqiang, Scheraga, Harold A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677636/
https://ncbi.nlm.nih.gov/pubmed/19344116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802362t
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