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The Oxidative Folding Pathway of Onconase, a Ribonuclease Homolog; Insight into Oxidative Folding Mechanisms From a Study of Two Homologs
The oxidative folding pathways of two four-disulfide proteins of the ribonuclease family, ONC and RNase A, which have similar three-dimensional folds but only 30 % sequence homology, are compared. In this study, a mechanism for the oxidative folding pathway of ONC is proposed. In particular, the kin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717042/ https://ncbi.nlm.nih.gov/pubmed/19309163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802327j |
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