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Implementation of a k/k(0) method to identify long-range structure in transition states during conformational folding/unfolding of proteins
A previously-introduced kinetic-rate constant (k/k(0)) method, where k and k(0) are the folding (unfolding) rate constants in the mutant and the wild-type forms, respectively, of a protein, has been applied to obtain qualitative information about structure in the transition state (TS) ensemble of bo...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2131734/ https://ncbi.nlm.nih.gov/pubmed/17937908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.08.003 |
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