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PROTEINASE ACTIVITY AND RECEPTOR CLEAVAGE: MECHANISM FOR INSULIN RESISTANCE IN SPONTANEOUSLY HYPERTENSIVE RAT
Arterial hypertension is associated with organ dysfunctions, but the mechanisms are uncertain. We hypothesize that enhanced proteolytic activity in the microcirculation of spontaneously hypertensive rats (SHRs) may be a pathophysiological mechanism causing cell membrane receptors cleavage and examin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677556/ https://ncbi.nlm.nih.gov/pubmed/18606910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.107.104356 |
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