Enhanced Matrix Metalloproteinase Activity in the Spontaneously Hypertensive Rat: VEGFR-2 Cleavage, Endothelial Apoptosis, and Capillary Rarefaction

Besides an elevated blood pressure, the spontaneously hypertensive rat (SHR) has multiple microvascular complications including endothelial apoptosis with capillary rarefaction. The SHR also has elevated levels of proteolytic (e.g. matrix metalloproteinase, MMP) activity and apoptosis in microvascul...

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Bibliografische gegevens
Hoofdauteurs: Tran, Edward D., DeLano, Frank A., Schmid-Schönbein, Geert W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2010
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2968763/
https://ncbi.nlm.nih.gov/pubmed/20145415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000281582
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