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Enhanced Matrix Metalloproteinase Activity in the Spontaneously Hypertensive Rat: VEGFR-2 Cleavage, Endothelial Apoptosis, and Capillary Rarefaction

Besides an elevated blood pressure, the spontaneously hypertensive rat (SHR) has multiple microvascular complications including endothelial apoptosis with capillary rarefaction. The SHR also has elevated levels of proteolytic (e.g. matrix metalloproteinase, MMP) activity and apoptosis in microvascul...

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Hlavní autoři: Tran, Edward D., DeLano, Frank A., Schmid-Schönbein, Geert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2968763/
https://ncbi.nlm.nih.gov/pubmed/20145415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000281582
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