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Matrix metalloproteinases cleave the β(2)-adrenergic receptor in spontaneously hypertensive rats
We recently observed the enhanced serine and matrix metalloproteinase (MMP) activity in the spontaneously hypertensive rat (SHR) compared with its normotensive Wistar-Kyoto (WKY) rat and the cleavage of membrane receptors in the SHR by MMPs. We demonstrate in vivo that MMP-7 and MMP-9 injection lead...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904131/ https://ncbi.nlm.nih.gov/pubmed/20382857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00620.2009 |
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