Genome-Wide Loss of Heterozygosity and Uniparental Disomy in BRCA1/2-Associated Ovarian Carcinomas

PURPOSE: The importance of the BRCA gene products in maintaining genomic stability led us to hypothesize that BRCA-associated and sporadic ovarian cancers would have distinctive genetic profiles despite similarities in histologic appearance. EXPERIMENTAL DESIGN: A whole-genome copy number analysis o...

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Hlavní autoři: Walsh, Christine S., Ogawa, Seishi, Scoles, Daniel R., Miller, Carl W., Kawamata, Norihiko, Narod, Steven A., Koeffler, H. Phillip, Karlan, Beth Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677417/
https://ncbi.nlm.nih.gov/pubmed/19047089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1291
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