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Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms
C-CBL (CBL) encodes a multifunctional protein engaged in the regulation of intracellular signaling pathways.(1,2) It was first identified as a cellular counterpart of the viral oncogene, v-CBL, that causes murine lymphoma.(3,4) Although no genetic evidence existed suggesting its role in human carcin...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880622/ https://ncbi.nlm.nih.gov/pubmed/20237427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.6.11034 |
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