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Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms

C-CBL (CBL) encodes a multifunctional protein engaged in the regulation of intracellular signaling pathways.(1,2) It was first identified as a cellular counterpart of the viral oncogene, v-CBL, that causes murine lymphoma.(3,4) Although no genetic evidence existed suggesting its role in human carcin...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Ogawa, Seishi, Sanada, Masashi, Shih, Lee-Young, Suzuki, Takahiro, Otsu, Makoto, Nakauchi, Hiromitsu, Koeffler, H. Philip
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880622/
https://ncbi.nlm.nih.gov/pubmed/20237427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.6.11034
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