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Prognostic relevance of acquired uniparental disomy in serous ovarian cancer

BACKGROUND: Acquired uniparental disomy (aUPD) can lead to homozygosity for tumor suppressor genes or oncogenes. Our purpose is to determine the frequency and profile aUPD regions in serous ovarian cancer (SOC) and investigated the association of aUPD with clinical features and patient outcomes. MET...

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Publicado en:Mol Cancer
Main Authors: Tuna, Musaffe, Ju, Zhenlin, Smid, Marcel, Amos, Christopher I, Mills, Gordon B
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320828/
https://ncbi.nlm.nih.gov/pubmed/25644622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0289-1
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