Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy

BACKGROUND: T-cell prolymphocytic leukemia is a rare aggressive lymphoproliferative disease with a mature T-cell phenotype and characteristic genomic lesions such as inv(14)(q11q34), t(14;14)(q11;q32) or t(X;14)(q28;q11), mutation of the ATM gene on chromosome 11 and secondary alterations such as de...

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Autors principals: Nowak, Daniel, Le Toriellec, Emilie, Stern, Marc-Henri, Kawamata, Norihiko, Akagi, Tadayuki, Dyer, Martin J., Hofmann, Wolf-Karsten, Ogawa, Seishi, Koeffler, H. Phillip
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663615/
https://ncbi.nlm.nih.gov/pubmed/19278963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001347
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