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Function-Oriented Synthesis: Biological Evaluation of Laulimalide Analogues Derived from a Last Step Cross Metathesis Diversification Strategy

Laulimalide is a potent microtubule stabilizing agent and a promising anticancer therapeutic lead. The identification of stable, efficacious and accessible analogues is critical to clinically exploiting this novel lead. To determine which structural features of laulimalide are required for beneficia...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mooberry, Susan L., Hilinski, Michael K., Clark, Erin A., Wender, Paul A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676913/
https://ncbi.nlm.nih.gov/pubmed/18662015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800043n
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