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New insight into serpin polymerization and aggregation

We recently solved the crystallographic structure of a dimeric form of the serpin antithrombin which has fundamentally changed the way we think about serpin polymerization. Like for other diseases that have protein deposition as a hallmark, the serpinopathies are associated with discrete inter-proto...

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Detalhes bibliográficos
Main Authors: Huntington, James A, Sendall, Timothy J, Yamasaki, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676738/
https://ncbi.nlm.nih.gov/pubmed/19372754
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