Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's disease (AD). The basis for the profuse accumulation of autophagic vacuoles (AVs) in affected neurons of the AD brain, however, is unknown. In this study, we show that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boland, Barry, Kumar, Asok, Lee, Sooyeon, Platt, Frances M., Wegiel, Jerzy, Yu, W. Haung, Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676733/
https://ncbi.nlm.nih.gov/pubmed/18596167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0800-08.2008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados