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Promoting Autophagic Clearance: Viable Therapeutic Targets in Alzheimer’s Disease

Many neurodegenerative disorders are characterized by the aberrant accumulation of aggregate-prone proteins. Alzheimer’s disease (AD) is associated with the buildup of β-amyloid peptides and tau, which aggregate into extracellular plaques and neurofibrillary tangles, respectively. Multiple studies h...

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Bibliographic Details
Published in:Neurotherapeutics
Main Authors: Friedman, Lauren G., Qureshi, Yasir H., Yu, Wai Haung
Format: Artigo
Language:Inglês
Published: Springer US 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322072/
https://ncbi.nlm.nih.gov/pubmed/25421002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-014-0320-z
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