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Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy

Targeting the amyloid‐β (Aβ) peptide cascade has been at the heart of therapeutic developments in Alzheimer's disease (AD) research for more than 25 years, yet no successful drugs have reached the marketplace based on this hypothesis. Nevertheless, the genetic and other evidence remains strong,...

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Foilsithe in:Br J Pharmacol
Main Authors: Nalivaeva, Natalia N., Turner, Anthony J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715594/
https://ncbi.nlm.nih.gov/pubmed/30710367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14593
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