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Plasmin-mediated Proteolysis Is Required for Hepatocyte Growth Factor Activation during Liver Repair

The physiological relevance of the activation of hepatocyte growth factor (Hgf) by the plasminogen (Plg) system of proteases and its contribution to tissue repair are largely undefined. Here, we investigated whether the defective liver repair in mice lacking Plg is due to impaired activation of Hgf....

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Main Authors: Shanmukhappa, Kumar, Matte, Ursula, Degen, Jay L., Bezerra, Jorge A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676022/
https://ncbi.nlm.nih.gov/pubmed/19286661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807313200
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