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Plasmin-mediated Proteolysis Is Required for Hepatocyte Growth Factor Activation during Liver Repair

The physiological relevance of the activation of hepatocyte growth factor (Hgf) by the plasminogen (Plg) system of proteases and its contribution to tissue repair are largely undefined. Here, we investigated whether the defective liver repair in mice lacking Plg is due to impaired activation of Hgf....

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Hlavní autoři: Shanmukhappa, Kumar, Matte, Ursula, Degen, Jay L., Bezerra, Jorge A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676022/
https://ncbi.nlm.nih.gov/pubmed/19286661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807313200
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