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Interdomain Flexibility in Full-length Matrix Metalloproteinase-1 (MMP-1)

The presence of extensive reciprocal conformational freedom between the catalytic and the hemopexin-like domains of full-length matrix metalloproteinase-1 (MMP-1) is demonstrated by NMR and small angle x-ray scattering experiments. This finding is discussed in relation to the essentiality of the hem...

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Detalhes bibliográficos
Main Authors: Bertini, Ivano, Fragai, Marco, Luchinat, Claudio, Melikian, Maxime, Mylonas, Efstratios, Sarti, Niko, Svergun, Dmitri I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676012/
https://ncbi.nlm.nih.gov/pubmed/19282283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809627200
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