The Structural Basis for Matrix Metalloproteinase 1 Catalyzed Collagenolysis

The proteolysis of collagen triple-helical structure (collagenolysis) is a poorly understood yet critical physiological process. Presently, matrix metalloproteinase 1 (MMP-1) and collagen triple-helical peptide models have been utilized to characterize the events and calculate the energetics of coll...

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Bibliographic Details
Main Authors: Bertini, Ivano, Fragai, Marco, Luchinat, Claudio, Melikian, Maxime, Toccafondi, Mirco, Lauer, Janelle L., Fields, Gregg B.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298817/
https://ncbi.nlm.nih.gov/pubmed/22239621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208338j
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