Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells

Membrane type-1 matrix metalloproteinase (MT1-MMP) is an activator of soluble MMP-2. The activity of both MMPs is regulated by their physiological inhibitor TIMP-2. An MT1-MMP/MMP-2/TIMP-2 axis plays a key role in the invasive behavior of many cell types. Despite its importance, epigenetic control o...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Chernov, Andrei V., Sounni, Nor Eddine, Remacle, Albert G., Strongin, Alex Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Transcription, Chromatin, and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676002/
https://ncbi.nlm.nih.gov/pubmed/19286653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900273200
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