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Regulatory Light Chain Mutations Associated with Cardiomyopathy Affect Myosin Mechanics and Kinetics

The myosin regulatory light chain (RLC) wraps around the alpha helical neck region of myosin. This neck region has been proposed to act as a lever arm, amplifying small conformational changes in the myosin head to generate motion. The RLC serves an important structural role, supporting the myosin ne...

詳細記述

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書誌詳細
主要な著者: Greenberg, Michael J., Watt, James D., Jones, Michelle, Kazmierczak, Katarzyna, Szczesna-Cordary, Danuta, Moore, Jeffrey R.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675789/
https://ncbi.nlm.nih.gov/pubmed/18929571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.09.126
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