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The Unnatural Substrate Repertoire of A, B, and X Family DNA Polymerases

As part of an effort to develop unnatural base pairs that are stable and replicable in DNA, we have examined the ability of five different polymerases to replicate DNA containing four different unnatural nucleotides bearing predominantly hydrophobic nucleobase analogs. The unnatural pairs were devel...

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Autors principals: Hwang, Gil Tae, Romesberg, Floyd E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675700/
https://ncbi.nlm.nih.gov/pubmed/18847263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803833h
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