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Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2)
The ubiquitin-conjugating enzyme E2-25K has been identified as a huntingtin (the key protein in Huntington’s disease) interacting protein and has been shown to play a role in mediating the toxicity of Aβ, the principal protein involved in Alzheimer’s disease pathogenesis. E2-25K is a dual-domain pro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2675580/ https://ncbi.nlm.nih.gov/pubmed/19407372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109011117 |
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