Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca(2+)-ATPase Expression in Cystic Fibrosis Airways: Role in Oxidant-mediated Cell Death

Rationale: Modulation of the activity of sarcoendoplasmic reticulum calcium ATPase (SERCA) can profoundly affect Ca(2+) homeostasis. Although altered calcium homeostasis is a characteristic of cystic fibrosis (CF), the role of SERCA is unknown. Objectives: This study provides a comprehensive investi...

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Detalhes bibliográficos
Main Authors: Ahmad, Shama, Ahmad, Aftab, Dremina, Elena S., Sharov, Victor S., Guo, Xiaoling, Jones, Tara N., Loader, Joan E., Tatreau, Jason R., Perraud, Anne-Laure, Schöneich, Christian, Randell, Scott H., White, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
D. Cystic Fibrosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675566/
https://ncbi.nlm.nih.gov/pubmed/19201925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200807-1104OC
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