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The inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by macrocyclic lactones and cyclosporin A.

The pharmacology of macrocyclic lactones is varied, with many beneficial effects in treating disease processes. FK-506, rapamycin and ascomycin have been utilized as immunosuppressant agents. Ivermectin is typically used to treat parasitic worm infections in mammals. Another immunosuppressant, cyclo...

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Bibliografiska uppgifter
Huvudupphovsmän: Bilmen, Jonathan G, Wootton, Laura L, Michelangeli, Francesco
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222768/
https://ncbi.nlm.nih.gov/pubmed/12022919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020431
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