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Stimulation of the Ca(2+)-ATPase of sarcoplasmic reticulum by disulfiram.

Disulfiram [bis(diethylthiocarbamoyl)disulphide] has been found to stimulate reversibly the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum. At pH 7.2, 2.1 mM ATP and 25 degrees C, ATPase activity was found to double on addition of 120 microM disulfiram. Stimulation fitted to binding of disu...

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Bibliografiske detaljer
Main Authors: Starling, A P, East, J M, Lee, A G
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217903/
https://ncbi.nlm.nih.gov/pubmed/8947473
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