The mechanism of inhibition of the Ca(2+)-ATPase of skeletal-muscle sarcoplasmic reticulum by the cross-linker o-phthalaldehyde.

Labelling the Ca(2+)-ATPase of skeletal-muscle sarcoplasmic reticulum with o-phthalaldehyde (OPA) results in loss of ATPase activity at a 1:1 molar ration of label to ATPase. The affinity of the ATPase for CA2+ is unaffected, as is the E1/E2 equilibrium constant. The rate of dissociation of Ca2+ fro...

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Hlavní autoři: Khan, Y M, Starling, A P, East, J M, Lee, A G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217507/
https://ncbi.nlm.nih.gov/pubmed/8713070
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