Transient in utero disruption of Cystic Fibrosis Transmembrane Conductance Regulator causes phenotypic changes in Alveolar Type II cells in adult rats

BACKGROUND: Mechanicosensory mechanisms regulate cell differentiation during lung organogenesis. We have previously demonstrated that cystic fibrosis transmembrane conductance regulator (CFTR) was integral to stretch-induced growth and development and that transient expression of antisense-CFTR (ASC...

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Detalhes bibliográficos
Main Authors: Gad, Ashraf, Callender, Delon L, Killeen, Erin, Hudak, Joseph, Dlugosz, Malgosia A, Larson, Janet E, Cohen, J Craig, Chander, Avinash
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675516/
https://ncbi.nlm.nih.gov/pubmed/19335897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-24
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