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LAG-3 Regulates Plasmacytoid Dendritic Cell Homeostasis

LAG-3 is a CD4-related, activation-induced cell surface molecule expressed by various lymphoid cell types and binds to MHC class II with high affinity. We have previously shown that LAG-3 negatively regulates the expansion of activated T cells and T cell homeostasis, and is required for maximal regu...

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Bibliografske podrobnosti
Main Authors: Workman, Creg J., Wang, Yao, El Kasmi, Karim C., Pardoll, Drew M., Murray, Peter J., Drake, Charles G., Vignali, Dario A.A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675170/
https://ncbi.nlm.nih.gov/pubmed/19201841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800185
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