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Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

Cholesterol biosynthesis is among the most intensely regulated processes in biology. Synthetic rates vary over hundreds of fold depending on the availability of an external source of cholesterol. Studies of this feedback regulatory process have a rich history. The field began 75 years ago when Rudol...

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Autores principales: Brown, Michael S., Goldstein, Joseph L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674699/
https://ncbi.nlm.nih.gov/pubmed/18974038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800054-JLR200
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