Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

BACKGROUND: Despite best current therapy, up to 20% of pediatric patients with acute lymphoblastic leukemia (ALL) have a relapse. Recent genomewide analyses have identified a high frequency of DNA copy-number abnormalities in ALL, but the prognostic implications of these abnormalities have not been...

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Detalhes bibliográficos
Main Authors: Mullighan, Charles G., Su, Xiaoping, Zhang, Jinghui, Radtke, Ina, Phillips, Letha A.A., Miller, Christopher B., Ma, Jing, Liu, Wei, Cheng, Cheng, Schulman, Brenda A., Harvey, Richard C., Chen, I-Ming, Clifford, Robert J., Carroll, William L., Reaman, Gregory, Bowman, W. Paul, Devidas, Meenakshi, Gerhard, Daniela S., Yang, Wenjian, Relling, Mary V., Shurtleff, Sheila A., Campana, Dario, Borowitz, Michael J., Pui, Ching-Hon, Smith, Malcolm, Hunger, Stephen P., Willman, Cheryl L., Downing, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674612/
https://ncbi.nlm.nih.gov/pubmed/19129520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0808253
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