RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker α(ν)β(3) integrin with MR T(1) mapping

Cyclic Arg-Gly-Asp-D-Phe-Lys [c(RGDfK)] targeted poly(L-glutamic acid) (PGA)-(Gd-DO3A) conjugate with a biodegradable cystamine spacer was prepared and evaluated for in vivo detection of an angiogenesis biomarker, α(ν)β(3) integrin, in neoplastic tissues with T(1) mapping, a quantitative magnetic re...

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Main Authors: Ke, Tianyi, Jeong, Eun-Kee, Wang, Xuli, Feng, Yi, Parker, Dennis L, Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2007
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673968/
https://ncbi.nlm.nih.gov/pubmed/17722547
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