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Non-invasive evaluation of antiangiogenic effect in a mouse tumor model by DCE-MRI with Gd-DTPA cystamine copolymers

The efficacy of polydisulfide-based biodegradable macromolecular Gd(III) complexes, Gd-DTPA cystamine copolymers (GDCC), for assessing tumor microvascular characteristics and monitoring antiangiogenesis therapy was investigated in a mouse model using dynamic contrast-enhanced MRI (DCE-MRI). The mice...

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Detalhes bibliográficos
Main Authors: Wu, Xueming, Jeong, Eun-Kee, Emerson, Lyska, Hoffman, John, Parker, Dennis L., Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815092/
https://ncbi.nlm.nih.gov/pubmed/19958031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900153f
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