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Stability and biodistribution of a biodegradable macromolecular MRI contrast agent Gd-DTPA cystamine copolymers (GDCC) in rats
PURPOSE: The aim of this study was to evaluate stability and Gd tissue distribution of a biodegradable macromolecular MRI contrast agent, GDCC. METHODS: Kinetic stability of GDCC was evaluated based on transmetallation with endogenous metal ions Zn(2+) and Cu(2+) in rat plasma in comparison with Omn...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025703/ https://ncbi.nlm.nih.gov/pubmed/20393871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0131-9 |
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