Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39

Leukocyte and platelet accumulation at sites of cerebral ischemia exacerbate cerebral damage. The ectoenzyme CD39 on the plasmalemma of endothelial cells metabolizes ADP to suppress platelet accumulation in the ischemic brain. However, the role of leukocyte surface CD39 in regulating monocyte and ne...

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Autores principales: Hyman, Matthew C., Petrovic-Djergovic, Danica, Visovatti, Scott H., Liao, Hui, Yanamadala, Sunitha, Bouïs, Diane, Su, Enming J., Lawrence, Daniel A., Broekman, M. Johan, Marcus, Aaron J., Pinsky, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673847/
https://ncbi.nlm.nih.gov/pubmed/19381014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36433
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