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Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications
Dextran, a biocompatible, water-soluble polysaccharide, was modified at its hydroxyls with acetal moieties such that it became insoluble in water but freely soluble in common organic solvents enabling its use in the facile preparation of acid-sensitive microparticles. These particles degrade in a pH...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673804/ https://ncbi.nlm.nih.gov/pubmed/18630909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803947s |
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